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Revista Cubana de Ortopedia y Traumatología

versión On-line ISSN 1561-3100

Rev Cubana Ortop Traumatol vol.37 no.3 Ciudad de la Habana jul.-set. 2023  Epub 15-Abr-2024

 

Review article

Utility of 3d printing in orthopaedic: a systematic review

Valor de la impresión 3D en ortopedia: una revisión sistemática

0000-0003-4768-4000 Filberto1  * 

1Hospital General de Weda, Halmahera Central. Molucas del Norte, Indonesia

ABSTRACT

The use of 3-Dimensional (3D) printing in orthopaedics keeps pace with technical advancements. However, due to its novelty, few research have examined its application. Therefore, our study aimed to assess the utility of 3D printing in orthopaedics use. We conducted a systematic review study during the period of April-May. Article search was conducted in Google Scholar, National Center for Biotechnology Information, Clinical Key, Pubmed, and Science Direct. We included five publications with a total of 99 patients. Our findings indicate that the orthopaedic application and utilization of 3D printing technologies are expanding. Despite the relative paucity of evidence, these findings suggest the utility of 3D printing technology in a variety of intraoperative deformity correction applications.

Key words: 3D Printing; additive manufacturing; orthopaedic

RESUMEN

El uso de la impresión tridimensional (3D) en ortopedia sigue el ritmo de los avances técnicos. Sin embargo, debido a su novedad, pocas investigaciones han examinado su aplicación. Por lo tanto, el estudio tuvo como objetivo evaluar la utilidad de la impresión 3D en el uso ortopédico. Se realizó un estudio de revisión sistemática durante el período de abril a mayo. La búsqueda de artículos se realizó en Google Scholar, National Center for Biotechnology Information, Clinical Key, Pubmed y Science Direct. Se incluyeron cinco publicaciones con un total de 99 pacientes. Nuestros hallazgos indican que actualmente se expanden la aplicación ortopédica y la utilización de las tecnologías de impresión 3D. A pesar de la relativa escasez de evidencia, estos hallazgos sugieren la utilidad de la tecnología de impresión 3D en una variedad de aplicaciones de corrección de las deformidades intraoperatorias.

Palabras-clave: impresión 3D; fabricación aditiva; ortopédico

Introduction

In the course of the development of contemporary medicine, surgical planning has passed through a variety of distinct phases, which have paralleled the development of diagnostic imaging technology. In conjunction with advancements in image processing, modern acquisition methods such as computed tomography (CT) and magnetic resonance imaging (MRI) provide the surgeon with detailed reconstructions of the patient's anatomy, as opposed to the simple radiographs of the early 1900s. Due to 3D printing technology, we can now go from the virtual to the physical world.1)

This rapidly emerging technology uses CT or MRI data to build 3D reconstructed images of graspable objects. Thus, efficient patient-specific anatomical models can be produced. These can enhance a surgeon's understanding of the pathoanatomy of a patient and facilitate precise preoperative planning. The 3D-printed patient-specific guidelines can also aid in achieving accurate bone cuts, precise implant placement, and great surgical outcomes. Implants, casts, orthoses, and prosthetics can be customized to a patient's anatomy.2 We intend to investigate the publishing trends in utility of 3D printing in orthopaedic.

Method

A literature search was performed on Google Scholar, NCBI, Clinical Key, Pubmed, and Science Direct. All articles pertaining to 3D Printing utilization in orthopaedics were extracted using appropriate search phrases ("UTILITY OF 3D PRINTING IN ORTHOPAEDIC" AND ("UTILITY, 3D PRINTING, ORTHOPAEDIC"). No time or evidence constraints were applied due to 3D printing in orthopaedics is still relatively new and the current evidence is primarily of low quality. The titles and abstracts of all duplicate and unrelated manuscripts were checked, and they were excluded.

Study Age patient Patology

3D Printing primary

application

PRE-OP

3D primary

application

INTRA-OP

3D Printing Material Pre-Op Imaging CT Pre-Op Imaging MRI Qualitative Outcome Quantitatif outcomes
Baskov et al3 11.5 27 Proximal femoral deformity (congenital/ acquired) - Plastic polymer

-X-ray exposures

-Radiography

assessment: neck shaft angle, epidiaphysis angle, femoral anteversion

Zheng et al4 6.6 11 Developmental dysplasia of the hip (DDH), Neck of Femur (NOF) fracture - Polylactic acid (PLA) Proximal femoral epiphyseal growth arrest

-Operation duration

-X-ray exposures

-Radiography

assessment: neck shaft angle, femoral anteversion

Zheng et al5 10.9 25 Developmental dysplasia of the hip (DDH) Polylactic acid (PLA) Proximal femoral epiphyseal growth arrest

-Operation duration

-X-ray exposures

-Radiographic assessment: neck shaft angle, femoral anteversion

Inge et al6 16.0 1 Distal radius malunion - - Union radiography

Clinical: ROM

DASH score

Hu et al7 7,5 35 Cubitus varus deformity (post-traumatic) Polylactic acid (PLA) Complications -Radiography union

-Operation duration

-Clinical: Elbow ROM, Deformity

-Radiographic assessment: Carrying angle

Results

From the five included research, it is evident that 3D printing has begun to be utilized intraoperatively in the orthopedic field. The majority of 3D printing components are Polylactic acid (PLA), while some research does not specify the constituents. Baskov et al.,3) Zheng et al.4) and Zheng et al.5) recorded usage for the femur, whereas Inge et al.,6 and Hu et al.,7 recorded use for the Radius and Humerus, respectively. The most frequently cited benefits of 3D printing are reduced operation times and x-ray exposure.

Discussion

The most important conclusion from the five studies is that intra-operation 3D printing reduces surgical operative time, fluoroscopic exposure, and blood loss. This outcome is consistent with adult population data collection.8 The most important quantitative outcomes were surgical operating time, fluoroscopy exposure, intraoperative blood loss, and radiographic data. Clinical examination indicators (such as joint stability, activity level, and discomfort) and surgical sequelae (such as avascular necrosis) were evaluated as qualitative outcomes. The comparative analysis did not identify a statistically significant effect in the pre-implementation study. However, improvements in qualitative results in terms of clinical assessment and complication rate have been documented.9

Three-dimensional scanning or 3D scanning is the process of retrieving data in the form of the geometry of an object to reconstruct the shape and 3D modelling of the object. The resulting 3D model is a collection of points arranged in the 3D space of the scanned object.10 The way 3D scan works is similar to a camera but uses more laser scanning, periphery projection, and photogrammetry (aerial mapping) methods. In many sectors, this leads to a 3D measurement approach and a virtual reconstruction of item surfaces. Generally, 3D scanning technologies function best on white or brightly colored object surfaces, which reflect light strongly. The 3D scan tool emits a laser to the object being scanned, then records the laser light reflected off the object's surface, and then the reflected light is processed into a collection of dots that make up the object being scanned.11

3D Printing, also known as additive manufacturing, is the process of creating or fabricating three-dimensional items using 3D models based on electronic data. Object models are 3D-printed using an additive process in which successive layers of material are added under computer control. 3D models (STL format) of the required objects are essential for this process.12

Utilization of 3D printing and additive manufacturing is anticipated to increase in the medical business. The utilization of technology in the production of orthosis prostheses and even human organs is becoming increasingly standardized. This market is still in its infancy, but it is anticipated that the usage of 3D Print in the medical field will expand. The 3D Print machine requires computer-aided design (CAD) data from the patient's anatomy to be realized in a physical model, so it needs to be preceded by the data acquisition process. Data acquisition is carried out by scanning the patient's anatomy using a 3D scanner or high-resolution medical imaging technology such as CT, MRI, etc. Then the acquired data will be processed in the form of image processing to create virtual models through dynamic and interactive simulations using CAD applications. Then the model is converted into a CAD .STL (stereolithography) file format. This G-code will then create .STL file to operate the 3D Print machine to produce shapes according to the model on the computer.13

Widely recognized are the advantages of 3D printing in comprehending complex abnormalities and gaining a better understanding of the treatment conditions.14 In pre-operative studies, surgeons can mimic 3D use procedures and better comprehend the 3D anatomy of the patient while deciding the appropriate size.9

In the diverse systematic study conducted by Levesque et al. in 2020, the application of 3D printing for pre-operative planning was the most prevalent, affecting a considerable proportion of the adult population.8

Conclusion

Orthopaedic use and utilization of 3D printing technologies are developing. Despite the relatively small evidence pool, these results imply the benefits of 3D printing technology in various deformity correction applications, particularly when applied "intraoperatively." To determine the potential benefits of 3D assessments, additional orthopaedics-specific high-quality research is required.

References

1.  Auricchio F, Marconi S. 3D printing: Clinical applications in orthopaedics and traumatology. EFORT Open Rev. 2016;1(5):121-7. DOI:https://doi.org/10.1302/2058-5241.1.0000121.  [ Links ]

2.  Vaishya R, Patralekh MK, Vaish A, Kumar A, Vijay V. Publication trends and knowledge mapping in 3D printing in orthopaedics. J Clin Orthop Trauma. 2018;9(3):194-201. DOI:https://doi.org/10.1016/j.jcot.2018.07.0062.  [ Links ]

3.  Baskov VE, Baindurashvili AG, Filippova AV, Barsukov D, Krosnov A, Pozdnikin I, et al. Planning corrective osteotomy of the femoral bone using three-dimensional modeling. Part II. Pediatr Traumatol Orthop Reconstr Surg. 2017;5(3):74-9. DOI:https://doi.org/10.17816/PTORS5374-793.  [ Links ]

4.  Zheng P, Yao Q, Xu P, Wang L. Application of computer-aided design and 3D-printed navigation template in Locking Compression Pediatric Hip Plate?? placement for pediatric hip disease. Int J Comput Assist Radiol Surg. 2017;12:865-71. DOI:https://doi.org/10.1007/s11548-017-1535-34.  [ Links ]

5.  Zheng P, Xu P, Yao Q, Tang K, Lou Y. 3D-printed navigation template in proximal femoral osteotomy for older children with developmental dysplasia of the hip. Sci Rep. 2017;7:44993. DOI:https://doi.org/10.1038/srep449935.  [ Links ]

6.  Inge S, Brouwers L, van der Heijden F, Bemelman M. 3D printing for corrective osteotomy of malunited distal radius fractures: a low-cost workflow. BMJ Case Rep. 2018;2018: bcr2017223996. DOI:https://doi.org/10.1136/bcr-2017-2239966.  [ Links ]

7.  Hu X, Zhong M, Lou Y, Peng X, Jiang B, Fengyong M, et al. Clinical application of individualized 3D-printed navigation template to children with cubitus varus deformity. J Orthop Surg Res. 2020;15:111. DOI:https://doi.org/10.1186/s13018-020-01615-87.  [ Links ]

8.  Levesque JN, Shah A, Ekhtiari S, Yan JR, Thornley P, Williams DS. Three-dimensional printing in orthopaedic surgery: a scoping review. EFORT Open Rev. 2020;5(7):430-41. DOI:https://doi.org/10.1302/2058-5241.5.1900248.  [ Links ]

9.  Cherkasskiy L, Caffrey JP, Szewczyk AF, Cory E, Bomar JD, Farnsworth CL, et al. Patient-specific 3D models aid planning for triplane proximal femoral osteotomy in slipped capital femoral epiphysis. J Child Orthop. 2017;11(2):147-53. DOI:https://doi.org/10.1302/1863-2548-11-1702779.  [ Links ]

10.  Koyuncu B, Kullu K, Binasi S, Blok A. Development of an optical 3D scanner based on structured light. 9thWSEAS International Conference on Artificial Intelligence, Knowledge Engineering and Data Bases. Cambridge, Kanada; 2010. pp 20-22. [access 03/05/2022]. Available from: Available from: http://www.wseas.us/e-library/conferences/2010/Cambridge/AIKED/AIKED-01.pdf 10.  [ Links ]

11.  Constantinou G, Wilson G, Sadeghi-Esfahlani S, Cirstea M. An effective approach to the use of 3D scanning technology which shortens the development time of 3D models. 2017 International Conference on Optimization of Electrical and Electronic Equipment (OPTIM). Brasov, Romania; 2017. pp. 1083-1088 DOI:https://doi.org/10.1109/OPTIM.2017.797511611.  [ Links ]

12.  Attaran M. The rise of 3-D printing: The advantages of additive manufacturing over traditional manufacturing. Bus Horiz. 2017;60(5):677-88. DOI:https://doi.org/10.1016/j.bushor.2017.05.01112.  [ Links ]

13.  Wang P, Yang J, Hu Y, Huo J, Feng X. Innovative design of a helmet based on reverse engineering and 3D printing. Alex Eng J. 2021;60(3):3445-53 DOI:https://doi.org/10.1016/j.aej.2021.02.00613.  [ Links ]

14.  Starosolski ZA, Kan JH, Rosenfeld SD, Krishnamurthy R, Annapragada A. Application of 3-D printing (rapid prototyping) for creating physical models of pediatric orthopedic disorders. Pediatr Radiol 2014;44:216-21. DOI:https://doi.org/10.1007/s00247-013-2788-914.  [ Links ]

Received: August 01, 2022; Accepted: August 06, 2022

*Corresponding author: drfilberto@gmail.com

The authors declare that there is no conflict of interest.

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