PASCUAL FRIAS, Carlos Enrique; DIAZ PADILLA, Belniu; PISONERO SOCIAS, Juan José    GUANCHE GARCELL, Humberto. Evolution of the Recommendations for Preventing Surgical Site Infection After Colon Surgery. []. , 59, 1   15--2020. ISSN 1561-2945.

Surgical site infections are a concern with respect to quality of health care. Surgical site infections are potentially preventable through the application of evidence-based prevention guidelines. The aim is to describe the historical evolution of practicing prophylactic use of antibiotics in colon surgery since the last century. We analyzed the literature published in the last five decades in MEDLINE, Infomed and other secondary sources. The evolution is highlighted of the combined use of antimicrobials (aminoglycosides, penicillin, cephalosporins, and nitroimidazoles) associated with the vigorous preparation of the colon in the 1970s of the last century. Numerous antimicrobials and practices have been tested to demonstrate that the use of antibiotics to control aerobic and anaerobic bacteria, administered orally and intravenously, achieves the prevention of up to 75% of surgical site infections in colon surgery. Scientific evidence points to the need for the use of more intravenous oral antibiotic prophylaxis associated with mechanical preparation of the colon.

: surgery; colon; prophylaxis; antibiotic; mechanical preparation; prevention; surgical site infection.

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