ARREDONDO BRUCE, Alfredo; AMORES CARRATE, Jacqueline; GUERRERO JIMENEZ, Gustavo    REYES OLIVA, Roberto. Gastroesophageal reflux disease: an entity to take into account. []. , 13, 3, pp. 0-0. ISSN 1025-0255.

The pathogenesis of the reflux esophagitis is fundamentally related to the rupture of normal defense mechanisms that avoid the pass in excess of gastric acid or pepsin to the inferior portion of the esophagus. This involves a series of defects of the antireflux and esophageal cleaning mechanisms. The knowledge of these subjacent, structural, functional, cellular and molecular components of the reflux esophagitis pathogeny will help us to improve the management of this entity and this way to avoid its progression.

: Esophagitis; gastric acid; pepsin.

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