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Revista Médica Electrónica
On-line version ISSN 1684-1824
Abstract
BLANCO-HERNANDEZ, Laudys Rosa. Management of gestational trophoblastic neoplasia. About a case. Rev.Med.Electrón. [online]. 2024, vol.46 Epub Jan 30, 2024. ISSN 1684-1824.
Gestational trophoblastic disease is defined as a heterogeneous group of lesions, which arise from the trophoblastic epithelium of the placenta after abnormal fertilization. The case of a 35-year-old female patient is presented with a diagnosis of posmolar gestational trophoblastic neoplasia in stage I, which was detected after follow-up imaging studies and determination of human chorionic gonadotropin, for which she underwent chemotherapy treatment and maintenance therapy with methotrexate for 5 days or methotrexate/folinic acid for 8 days, until normalization of human chorionic gonadotropin The most relevant thing is that, although these tumors comprise less than 1% of gynecological tumors, they represent a threat to the life of women of reproductive age.
Keywords : gestational trophoblastic disease; posmolar gestational trophoblastic neoplasia; human chorionic gonadotropin hormone; Methotrexate; folinic acid.