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Revista Cubana de Reumatología
On-line version ISSN 1817-5996
Abstract
BARBA CARRILLO, Génesis Leonor; SANDOVAL GOMEZ, Sebastián Alejandro; GONZALEZ CALVA, Laura Elizabeth and SARABIA SOLIS, Denisse Alexandra. Prescription of gastric protectors in rheumatological patients: Analysis from a gastroenterology outpatient clinic. Rev Cuba Reumatol [online]. 2022, vol.24, n.2 Epub Oct 01, 2022. ISSN 1817-5996.
Introduction:
Nonsteroidal anti-inflammatory drugs are the most prescribed medications by rheumatologists and traumatologists. However, despite having similar efficacy in controlling inflammation and pain, the different available nonsteroidal anti-inflammatory drugs show variability in their safety profile.
Objective:
To provide an overview of the prescription of gastric protectors in rheumatological patients, in two hospital centers, from a gastroenterological perspective.
Methods:
The research is part of the quantitative paradigm with an observational study. Two groups of patients were formed, one of them from hospital A and the second group belonged to hospital B.
Discussion:
Gastroprotectors have become the drugs in greatest demand in community pharmacies in Ecuador, the most prescribed being Proton Pump Inhibitors (IBPS) and, to a lesser extent, H2 antihistamines (anti-H2). Regarding the most frequently prescribed gastroprotectors, according to our study, these values could be due to the availability and costs of famotidine and omeprazole compared to other drugs with proven effectiveness, such as ansoprazol, pantoprazole, rabeprazole and ranitidine.
Conclusions:
In recent years, the use of gastroprotective drugs in Latin America has undergone significant development, with the observance of clinical case management norms and guidelines that offer important recommendations in this regard. Therefore, from a gastroenterological perspective, to be successful, it is essential to seek knowledge of these contributions and scientific evidence.
Keywords : nonsteroidal anti-inflammatory drugs; gastric protectors; variability of the safety profile; rheumatological patients; external consultation; prescription; gastroenterological perspective.