Introduction:

A plethora of symptoms/signs have been described that clearly indicate that COVID-19 is a complex disease, and a growing number of reports have suggested that ABO blood groups are related to the risk of developing the disease.

Objective:

to identify if there is a relationship between the blood phenotypes of the ABO system and the clinical manifestations of Covid-19 in a health area in the Bayamo municipality.

Methods:

a retrospective descriptive study was carried out, which included 123 confirmed COVID-19 patients with epidemiological discharge. Blood group was determined according to the ABO system. The subjects were classified according to the number of symptoms/signs, the predominance of respiratory symptoms/signs or not. The association between the blood groups of the ABO system, the carriers of the different antigens in comparison with those of those without the antigen and the groups by number of symptoms and signs, and according to predominance or not of respiratory symptoms/signs was analyzed.

Results:

a significant association was found between the blood group of the patients and the groups according to the number of symptoms/signs presented, as well as between carriers of B and non-B antigens and the groups according to the number of symptoms/signs presented and the predominance of respiratory symptoms or not, in all cases with a higher frequency of patients with phenotype A.

Conclusions:

it is concluded that in this study the blood group of patients positive for Covid-19 was related to the number of symptoms/signs presented, with a predominance of the frequency of carriers of antigen A over the others.

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