Introduction:

the world deals with a new pandemic because of SARS-CoV-2 outbreak initiated in Wuhan, China in December 2019. Host genetic differences and risk factors such as: personal history, lifestyles and environmental factors may contribute to the marked inter-individual clinical variability in COVID-19.

Objective:

to identify personal pathological history (chronic diseases and smoking) associated with SARS-CoV-2 infection.

Methods:

analytical, observational study of cases and controls in Pinar del Rio in the period from March 2020 to March 2021. Personal history of chronic diseases and smoking as an environmental factor were explored.

Results:

personal pathological history of allergies and asthma constituted risk factors to develop symptoms. History of active smoking is presented as a risk factor for infection.

Conclusions:

the contribution of personal pathological history (allergy and asthma) and environmental (active smoking) to SARS-CoV-2 infection and to the development of symptoms in COVID-19 patients in Pinar del Rio is confirmed.

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