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Gaceta Médica Espirituana
versión On-line ISSN 1608-8921
Resumen
REYES CEPERO, Yudania et al. Relation among gender and levels of C reactive protein. Gac Méd Espirit [online]. 2021, vol.23, n.1, pp. 56-65. Epub 01-Abr-2021. ISSN 1608-8921.
Background:
C-reactive protein is one of the best marker for the assessment and monitoring of inflammatory diseases; the recommended reference values for its serum concentration are not gender-adjusted.
Objective:
To determine whether C-reactive protein concentration differs by gender.
Methodology:
An exploratory study was conducted on 3199 patient samples from Camilo Cienfuegos General Provincial Hospital and a control group of 76 serum samples from blood donors of each gender from the Sancti Spíritus Blood Bank. Levels were measured by a semi-quantitative latex particle agglutination assay for the presumed diseased sample and a quantitative immunoturbidimetric assay for the presumed healthy sample. Mean levels were compared between genders in each using Student's t-test for independent samples.
Results:
The mean of C-reactive protein levels in the male and female gender of the supposedly diseased sample was 3.49 mg/L and 3.41 mg/L respectively. In the control group the mean comparison of C-reactive protein levels between genders was 1.38 mg/L for males and 1.94 mg/L for females.
Conclusion:
No significant gender differences were found in the presumed ill sample, nor in the control group.
Palabras clave : C-reactive protein; gender; semi-quantitative assay for agglutination with latex particles; quantitative immunoturbidemetric assay.