Resumen

GARCIA TRIANA, Bárbara E; GARCIA PINEIRO, José C  y  SALDANA BERNABEU, Alberto. La peroxidación lipídica en la etiopatogenia de la enfermedad periodontal inflamatoria. Rev Cubana Estomatol [online]. 1998, vol.35, n.1, pp. 25-29. ISSN 1561-297X.

The reative oxygen species are involved in the pathogenesis of inflammation. Leukocyte activation released a great amount of these species the function of which is to eliminate pathogen agents. If antioxidant tissue defenses do not act properly, then radical reactions affecting biomolecules are induced. The attack on cell membrane lipids caused their peroxidation followed by the formation of new radical species and toxic metabolites. The existence of a strong inflammatory infiltrate in periodontal tissues in the course of the periodontal disease suggest the possible involvement of reactive oxygen species in the pathogenesis of this disease. It is supposed that the attack of these substances on the poorly antioxidant defended periodontal tissues makes the lipid peroxidation take place, which may lead to cellular lysis and proteases activation.

Palabras clave : PERIODONTITIS [etiology]; LIPID PEROXIDATION; REACTIVE OXYGEN SPECIES; LEUKOCYTES.

        · resumen en Español     · texto en Español     · Español ( pdf )