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Revista Cubana de Medicina Militar
versión On-line ISSN 1561-3046
Resumen
SANCHEZ VERA, Naivy et al. Clinical laboratory parameters in patients with COVID-19. Rev Cub Med Mil [online]. 2021, vol.50, n.2 Epub 01-Ago-2021. ISSN 1561-3046.
Introduction:
Knowing the alterations in clinical laboratory tests is useful in the diagnosis and progress of patients with COVID-19.
Objective:
To describe the clinical laboratory parameters in patients diagnosed with COVID-19.
Methods:
Descriptive study in 82 hospitalized patients with COVID-19. The variables analyzed were age, sex, comorbidity, patient report, discharge status, hemoglobin, white blood cell count, absolute neutrophil count, absolute lymphocyte count, platelet count, erythrocyte sedimentation rate, D-dimer, creatinine, urea, alanine aminotransferase, aspartate aminotransferase, γ-glutamyl transpeptidase, alkaline phosphatase, lactate dehydrogenase, neutrophil / lymphocyte and platelet / lymphocyte ratio.
Results:
The average age was 55.61 ± 22.04, the majority were female (57.3%), hypertensive (41.5%), 18.3% reported serious and 14.6% died. Advanced age and comorbidity were associated with the severity report. There was a significant decrease in hemoglobin, lymphocytes; elevated erythrocyte sedimentation rate, D-dimer, creatinine, γ-glutamyl transpeptidase, and lactate dehydrogenase, especially in severe patients. The neutrophil / lymphocyte and platelet / lymphocyte ratio warned about the worsening of the patient and the possibility of death.
Conclusions:
The patients a mean age of 55.61, female, with arterial hypertension; they were discharged alive, reported as not serious. Mean hemoglobin values decrease, global lymphocyte count, especially in severe patients; increases D-dimer, creatinine, ALT, AST, ALP, GGT, and LD. The neutrophil / lymphocyte and platelet / lymphocyte ratio show high mean values, especially in severely ill patients and in those who died.
Palabras clave : laboratory parameters; COVID-19; SARS-CoV-2; biomarkers.