Introduction:

Neonatal infection is a clinical syndrome that constitutes an important cause of neonatal morbidity and mortality.

Objective:

to determine the relationship between some maternal and neonatal factors and the occurrence of early-onset infections tested in the neonatology service of the General University Teaching Hospital Carlos M. de Céspedes in the period from January 2014 to December 2019.

Methods:

an analytical investigation of cases and controls was carried out whose sample consisted of 450 neonates diagnosed with proven early infection and 900 controls with a ratio of 1 case to 2 controls.

Results:

in relation to maternal variables, the age of the mother, with O.R 1.74, an IC. 95% (1.28-2.34) with p:0.003, the gestational age less than 31 weeks an O.R: 2.14, and a p: 0.006, vaginal infection an OR: 5.19, and p: 0.000, urinary infection OR: 4.99, and p: 0.000; dystocic delivery as a risk factor an OR: 0.98 y p: 0.923, the rest of the maternal variables such as membrane rupture time greater than 18 hours, abnormal amniotic fluid (fetid and / or purulent), the total time of prolonged labor and the politact p <0.05; clinical and histological chorioamnionitis with p <0.05; the weight of the neonate less than 1000 grams and 1000-1499 grams with p: 0.004 and 0.02 respectively, the male sex with OR: 1.82 and p: 0.000 and the Apgar score less than 7 at the first and fifth minute of life p <0.05.

Conclusions:

the maternal variables except dystocic delivery were significant, and the neonatal variables studied were significant.

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