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Revista Cubana de Angiología y Cirugía Vascular
versión On-line ISSN 1682-0037
Resumen
ALVAREZ HIDALGO, Roberto Jesús; ESCALANTE PADRON, Odalys y ALVAREZ ESCALANTE, Gretel. Characterization of the immunometabolic status of patients with diagnosis of diabetic foot. Rev Cubana Angiol Cir Vasc [online]. 2020, vol.21, n.2 Epub 01-Ago-2020. ISSN 1682-0037.
Introduction:
Diabetic foot is a clinic alteration induced by persistent hyperglycemias, with or without ischemia and previous trauma, lesion and/or ulceration of the foot. Hyperglycemia favours infections, but it does not increase the bacterial growth which suggests the participation of the immune system in this sensitivity.
Objective:
To characterize the immunometabolic status of patients with diagnosis of diabetic foot.
Methods:
It was carried out a descriptive, cross-sectional study in 25 patients hospitalized with diagnosis of diabetic foot among September and December, 2018 in “Manuel Ascunce Domenech” University Hospital. The studied variables were: age, sex, clinical forms of diabetic foot, complement 3 and 4, G and A, immunoglobulins and glycosylated hemoglobine. It was used descriptive statistic for data analysis.
Results:
Females represented the 60% and patients older than 70 years were the 40%. Seric G immunoglobulin was found as decreased in 28% of the patients with diabetic foot and increased in the 28%. Glycosylated hemoglobine presented unbalanced in 48% of the cases. From the patients with metabolic decontrol, 8 (32%) showed alterations of G immunoglobulin and 2 in the component C3.
Conclusions:
There was a group of patients with diabetic foot who presented variable immunological alterations and/or metabolic decontrol. Those patients can benefit with an integral management using immunotherapy and the prevention of infectious complications of the diabetic foot.
Palabras clave : Diabetes mellitus; diabetic foot; immune status; metabolic control.