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Revista Cubana de Hematología, Inmunología y Hemoterapia
versión On-line ISSN 1561-2996
Resumen
ALFONSO VALDES, María Elena; BENCOMO HERNANDEZ, Antonio; HERNANDEZ PADRON, Carlos y AVILA CABRERA, Onel M. Cold agglutinins syndrome and autoimmune thrombocytopenic purpura: An unusual case of Evans syndrome. Rev Cubana Hematol Inmunol Hemoter [online]. 2015, vol.31, n.2, pp. 195-203. ISSN 1561-2996.
Evans syndrome is a rare disorder in which thrombocytopenia and anemia are observed, both of autoimmune aetiology, which may occur simultaneously or successively. A rare case of cold autoimmune hemolytic anemia associated to autoimmune thrombocytopenic purpura is presented. A 22-year-old female patient with diagnosis of autoimmune thrombocytopenic purpura, after 7 years of evolution and one year in remission, has a cold autoimmune hemolytic anemia, refractory to steroid treatment and vinca alkaloids, which requires transfusions of packed erythrocytes and achieves remission with anti CD 20 monoclonal antibody. The remaining studies of autoimmunity are negative. Currently the patient is asymptomatic and without immunosuppressive therapy.
Palabras clave : Evans syndrome; autoimmune hemolytic anemia cold antibody; cold agglutinins syndrome; CAS; autoimmune thrombocytopenic purpura.