Resumen

ALVAREZ CRESPO, Alina R.; ALONSO CARBONELL, Liuba; YERA ALOS, Isis  y  GARCIA MILIAN, Ana J.. Clinical progress of patients with diabetic foot ulcer treated with Heberprot-P®. AMC [online]. 2013, vol.17, n.5, pp. 544-557. ISSN 1025-0255.

Background: Heberprot-P®, prescribed for the treatment of diabetic foot ulcer, contributes to the re-establishment of the granulation tissue, being favorable to the cicatrisation process. Objective: to characterize the clinical progress of patients with diabetic foot ulcer treated with Heberprot-P®. Method: an observational, prospective, multicentric study of monitoring of the post-marketing of Heberprot-P® was conducted between June, 2007 and March, 2010 in Havana city. Results: the 53.1 % of the patients were female and the average age was 62.66 ± 11.758 years old. High blood pressure was the most frequent pathology in the patients with diabetic foot ulcer, being present in the 65 % of them. In the 75.2 % of the patients treated with Heberprot-P®, a complete granulation was observed. Diabetic foot ulcers were more frequent in the 66.1 % of the type II diabetic patients; the ulcers were on stage 3 and 4 of Wagner (39.5 % and 27.7 %, respectively). The 81.9 % of the patients used the dose of 75 µg. Conclusions: in around the three fourths of the medicated patients, a complete granulation was achieved; there was an association between it and the type of diabetes mellitus.

Palabras clave : DIABETIC FOOT [therapy]; GRANULATION TISSUE; CLINICAL EVOLUTION; REVIEW LITERATURE AS TOPIC.

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