Mi SciELO
Servicios Personalizados
Articulo
Indicadores
Citado por SciELO
Links relacionados
Similares en SciELO
Compartir
Revista Cubana de Anestesiología y Reanimación
versión On-line ISSN 1726-6718
Resumen
LABRADA DESPAIGNE, Alberto; RIVERA MARTI, Yailin y COSTA ORTIZ, Geydis. Tow concentrations of ketofol in total intravenous anesthesia for minimally invasive surgery. Rev cuba anestesiol reanim [online]. 2022, vol.21, n.3 Epub 01-Nov-2022. ISSN 1726-6718.
Introduction:
In recent years, a special interest has appeared in the ketamine/propofol combination for patients intervened by minimally invasive procedures.
Objective:
To evaluate the effectiveness and safety of total intravenous anesthesia with ketofol at 1:4 concentration versus 1:2 concentration in patients undergoing minimally invasive surgery.
Methods:
An analytical, quasiexperimental, prospective and longitudinal study was carried out at General Calixto García University Hospital, between December 2019 and December 2020, with thirty patients divided into two groups of fifteen patients each: study group (SG; ketofol 1:4) and control group (CG; ketofol 1:2). The following aspects were analyzed: mean blood pressure and intraoperative cardiac frequency, degree of hypnosis, degree of nociception, necessity of rescue for hypnosis and analgesia, anesthetic recovery time, postoperative analgesia and adverse effects.
Results:
Age, sex, weight, physical condition and type of surgery were similar between groups. Heart rate showed no differences between groups. Mean blood pressure after incision was higher in the control group, with significant differences (P=0.03). The necessity of intraoperative rescue for hypnosis and analgesia was significantly higher in the control group. Regarding anesthetic recovery, postoperative analgesia and adverse effects, there were no significant differences.
Conclusion:
The ketofol combination was safe and effective for providing adequate anesthesia in minimally invasive surgical procedures with surgical times of less than thirty minutes. The 1:4 concentration provided better hemodynamic stability, adequate hypnosis and intraoperative analgesia, with lower incidence of adverse effects.
Palabras clave : ketamine; propofol; minimally invasive surgical procedures; intravenous anesthesia.