Resumen

PORRATA MAURY, Carmen et al. Therapeutical effect of Ma-Pi2 macrobiotic diet on adults with type 2 diabetes mellitus. Rev Cubana Invest Bioméd [online]. 2007, vol.26, n.2, pp. 0-0. ISSN 1561-3011.

A clinical assay of 25 adults with type 2 diabetes mellitus, who were treated with anti-hyperglycemic drugs was conducted for six months in order to study the therapeutical effect of vegetarian macrobiotic diet Ma-Pi2. Data from dietetic surveys, clinical evolution, nutritional status, biochemical indicators, glucose and lipid metabolism indicators, drug consumption and adverse effects were evaluated. The diet mostly comprised whole grains, vegetables, leguminosae and green tea; sufficient energy, low fat and adequate protein contents, high amount of complex carbohydrates, dietetic fiber, ß carotene, manganese and magnesium. At the end of the study, glycemic levels lowered by 53 %, glycosylated hemoglobin by 32 %, cholesterol by 21 %, triglycerides by 43 % and LDL/HDL cholesterol ratio by 61 %. Body weight, and waist and hip circumferences were significantly reduced. Hemoglobin, creatinine, uric acid, urea, piruvic glutamic transaminase, heart rate and blood pressure values stabilized. Vitamin A, E, C, B₁, B₁₂ and folates serum levels were satisfactory. Of the total number of patients, 88% totally ceased their antihyperglycemic treatment. No adverse effects were observed. Improvement in associated symptoms, well-being and quality of life was remarkable. It was concluded that the Ma-pi2 diet proved to be a very suitable therapeutical alternative in the 25 studied patients with type 2 diabetes mellitus.

Palabras clave : Type 2 diabetes mellitus; adults; treatment; macrobiotic diet.