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Revista Cubana de Investigaciones Biomédicas

versión impresa ISSN 0864-0300

Resumen

OLIVARES AQUILES, Eddy W et al. Association between some cardiovascular risk factors and coronary calcium scoring in symptomatic patients. Rev Cubana Invest Bioméd [online]. 2012, vol.31, n.4, pp. 447-458. ISSN 0864-0300.

Introduction: knowledge of an individual's overall atherosclerotic burden is extremely important. Its association with cardiovascular risk factors has not been well established. Objective: determine the association between some cardiovascular risk factors and coronary calcium scoring. Methods: a study was conducted of 169 symptomatic patients with suspected ischemic heart disease. The patients consecutively underwent calcium scoring and risk factor identification. Association between the two values was determined by logistic regression modeling. Results: 106 patients were women and 63 were men; mean age was 59.6 ± 10.8 and 59.5 ± 11.0, respectively. 51.9 % of the women and 34.9 % of the men had a score = 0. Mean effective radiation dose was 0.82 mSv. The variables male patient aged > 55, female patient aged > 65, smoking, diabetes mellitus, age, number of risk factors, VLDL, triglycerides and HDL showed a significant association with some of the calcium score cut-off values established. In the multivariate analysis, age, smoking, triglycerides and HDL as a protective factor, exhibited coefficients significantly different from 0, with age exerting the greatest influence upon the calcium score > 0 and ³ 100 value, and HDL upon the ³ 400 value. Conclusions: only some risk factors show an association with coronary calcium score, particularly age and HDL levels as a protective factor.

Palabras clave : factor; atherosclerosis; coronary calcium score; computed tomography.

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