Resumen

GARCIA-DIAZ, Jesús et al. Isolation and characterization of metabolites from Croton linearis Jacq. leaves. Rev Cub Quim [online]. 2015, vol.27, n.3, pp. 289-301. ISSN 2224-5421.

From an ethanolic extract of Croton linearis Jacq. leaves were isolated and identified a total of 7 compounds: two long chain alcohols: 2-methyl-tretradecan-2-ol (1) y el hexacosanol (3); a linear saturated hydrocarbon: tetracosane (2); three fatty acids: stearic (4), 5,8-dien-tetradecanoic (6) and oleic acid (7); as well as a tri-methoxylated flavone: 5-hydroxy-3,7,4'-trimethoxyflavone (5). Structures of the compounds were elucidated by spectroscopic techniques as Nuclear Magnetic Resonance 1D and 2D (¹H and ¹³C), as well as Gas Chromatography/Mass Spectrometry and Kovats retention indexes when necessary. The substituent positions were assigned based on combination of heteronuclear HMBC and HMQC as well as homonuclear ¹H-¹H-COSY experiments. All identified compounds constitute a first report for the specie in study.

Palabras clave : Croton linearis; metabolites; isolation; flavone.

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