Resumen

MOYA MACHADO, Ariel; HERNANDEZ GARCIA, Margarita  y  ESQUIVEL SOSA, Leidelen. Chronic Recurrent Multifocal Osteomyelitis: presentation of case. Rev Cuba Reumatol [online]. 2018, vol.20, n.1, pp. 1-10. ISSN 1817-5996.  http://dx.doi.org/10.5281/zenodo.1174359.

Autoinflammatory syndromes are a group of diseases characterized by spontaneous, recurrent or persistent episodes of multisystem inflammation. They do not show an infectious, neoplastic or autoimmune etiology. They are caused by alterations of the innate immunity, which causes a dysregulation of the inflammatory system at the level of the inflammasome. These syndromes are subdivided into two major groups, the hereditary syndromes of periodic fever and the persistent autoinflammatory diseases; within the latter are the inflammatory bone diseases which chronic recurrent multifocal osteomyelitis. We present a case of a 9-year-old girl who enters our hospital due to a prolonged febrile syndrome and after multiple investigations, it concludes as a Chronic Recurrent Multifocal Osteomyelitis.

Palabras clave : chronic recurrent multifocal osteomyelitis; CRMO; autoinflammatory disease; multiple osteolytic lesions.

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