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Revista Cubana de Cirugía
versión On-line ISSN 1561-2945
Resumen
CERVANTES PELAEZ, Dayan; FUENTES DIAZ, Zaily; NICOLAU PESTANA, Elizabeth y ESCALONA SANCHEZ, Yelandy. Effectiveness of Treating Secondary Anal Fissure with Platelet and Leukocyte-Rich Plasma. Rev Cubana Cir [online]. 2023, vol.62, n.4 Epub 10-Mar-2024. ISSN 1561-2945.
Introduction:
Platelet-rich plasma is a blood-derived product, rich in peptides and intercellular signaling proteins, as well as cytokines capable of intervening in each of the stages of regeneration of various tissues.
Objective:
To assess the effectiveness of treatment with platelet- and leucocyte-rich plasma in patients with secondary anal fissure who attended the coloproctology office at Hospital Docente Provincial Oncológico María Curie of Camagüey from January 2020 to January 2023.
Methods:
A quasiexperimental study was carried out, whose universe consisted of all the patients who came for consultation during that period. The nonprobabilistic purposive sample consisted of 130 adult patients with a diagnosis of secondary anal fissure who received treatment with platelet- and leucocyte-rich plasma.
Results:
The healing time of the anal fissure allowed corroborating the effectiveness of the treatment; in addition, most of the patients evolved favorably. Pain was the most visible complication since it presented statistical significance when the relationship between the variables were established. Treatment with platelet- and leucocyte-rich plasma in patients with secondary anal fissure proved effective and safe in the final assessment of the treatment.
Conclusions:
The above allows considering that the treated patients obtained good outcomes when making use of platelet- and leucocyte-rich plasma. Therefore, it has a positive outcome, not showing complications and a high possibility for the treated patient to evolve in a better condition.
Palabras clave : regenerative therapy; secondary anal fissure; plasma; platelet; leucocytes.