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Revista Habanera de Ciencias Médicas
versión On-line ISSN 1729-519X
Resumen
MORALES LEON, José Angel et al. Quality control of pharmaceutical formulations obtained from cassia uniflora mill. Rev haban cienc méd [online]. 2011, vol.10, n.4, pp. 532-539. ISSN 1729-519X.
Introduction: Cassia uniflora Mill has a high biological availability; It is used in treatments for spasmodic pains, cutaneous eruptions and some infections of bacteriological origin. The most useful parts are its leaves and seeds. Objectives: To determine the specifications of quality control for tinctures made up from leaves and seeds of Cassia uniflora Mill at 20%. Material and methods: Tincture at 20% was made up of the powders of leaves and seeds, using as menses a hydroethanolic solution. Determination of quality control specifications of the tinctures were made taking into account four parameters: pH, refraction index, total solids and relative density. Results: Data obtained in the quality control of the tinctures at 20% are among the ranks of quality established by the standards. Discussion: Quality parameters show that tinctures at 20% from leaves and seeds of Cassia uniflora Mill had no relevant changes that could affect its pharmacological quality, therefore they have a certain degree of stability. Conclusions: The specifications of the quality control made to the tinctures indicate that under the conditions applied the elaborated products are innocuous, so they are totally guaranteed for therapeutically use.
Palabras clave : Cassia uniflora Mill; quality control; pH; relative density; pharmaceutical formulations; tincture; innocuousness.