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Revista Habanera de Ciencias Médicas
versión On-line ISSN 1729-519X
Resumen
BORGES GONZALEZ, Susana Ángela et al. Health-related quality of life in patients with chronic hepatitis B and C virus infection. Rev haban cienc méd [online]. 2023, vol.22, n.2 Epub 01-Abr-2023. ISSN 1729-519X.
Introduction:
Health-related quality of life measured through "patient-reported outcomes" (PROs) allows effective detection of physical and psychological problems in patients with chronic hepatitis.
Objective:
To identify the quality of life outcomes reported by patients with chronic hepatitis C and B virus infection.
Material and Methods:
A descriptive, cross-sectional study was conducted from June 2018 to December 2020 at the Institute of Gastroenterology. Of 1 706 patients with chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infection, 366 adults were included in the sample. Data was collected using validated instruments: Functional Assessment for Chronic Illness Treatment-Fatigue Scale (FACIT-F) and Work Productivity and Activity Impairment Questionnaire: Specific Health Problem (WPAI-SPH). Clinical and demographic parameters were also recorded.
Results:
A total of 271 (74.0%) patients with HCV and 95 (26.0%) HBV diagnosis were identified, mean (SD) age 54.0 ± 12.7, and 209 (57.1%) women. The FACIT-F total score was more affected in HCV (FACIT-F: HBV: 129.0 ± 15.9 vs. HCV: 111.2 ± 23.5; p<0.0001); these patients also had greater impairment in work activity (WPAI-SPH: HBV: 0.309 ± 0.312 vs. HCV: 0.386 ± 0.333; p<0.05).
Conclusions:
Patients with HCV have a worse quality of life that compromises their well-being, work and daily performance.
Palabras clave : Quality of life; health-related quality of life; hepatitis; hepatitis C virus; hepatitis B virus.