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Revista Finlay
versión On-line ISSN 2221-2434
Resumen
DIAZ MOREJON, Lucía; RODRIGUEZ JORGE, Belkis y LEON RAYAS, Yoandra. Castleman Disease in Pediatrics. Case Presentation and Bibliography Review. Rev. Finlay [online]. 2019, vol.9, n.1, pp. 51-55. ISSN 2221-2434.
Castleman's disease is an uncommon condition with similar frequency in both sexes, which can appear at any age. It is characterized by the growth of benign tumors of the lymphatic tissue, located more frequently in the mediastinum, stomach and neck and are less frequent in the axilla, pelvis and pancreas. Histologically, three varieties are described: the hyaline-vascular, the plasma-cellular and the mixed. A case of a 13-year-old patient with a history of congenital micro-spherocytosis and cytomegalovirus infection is presented. He had frequent admissions due to prolonged febrile syndrome; the last one occurred at age 11, when an increase in the size of ganglion chains appeared, predominantly intra-abdominal ganglia. A histological study was performed that reported Castleman's disease with diffuse lymph node involvement, in addition to chronic reactive hepatitis. Currently the patient is maintained with outpatient follow-up with hematological control and abdominal ultrasound, as well as treatment with vitamin therapy. This report is presented due to the low prevalence of this type of tumor in University Pediatric Hospital Paquito González Cueto of Cienfuegos.
Palabras clave : castleman disease; adolescent; case reports..