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Revista Cubana de Estomatología
versión On-line ISSN 1561-297X
Resumen
RODRIGUEZ CALZADILLA, Orlando L. Manifestaciones mucocutáneas del liquen plano: Revisión bibliográfica. Rev Cubana Estomatol [online]. 2002, vol.39, n.2, pp. 157-186. ISSN 1561-297X.
Lichen planus is a skin and mucous disease that is relatively frequent. Mucous membrane lesions are white-coloured and persisted for years after the skin lesions have disappeared. The odontologist often diagnoses it because its first symptoms and signs occurred in the oral mucous membrane. It is characterized by a band inflammatory infiltrate and vacuolizing degeneration of the basal layer of epithelium, events that might indicate an autoimmune cell reaction as a basis of the process. Two important phenomena are described in the immune cell response: the leukocyte histocompatibility antigen expression (HLA-DR) and intercellular adhesion molecule-1 (ICAM-1). There have been reported cases of malignant transformation in erythematous or erosive lichen planus. The prognosis of lichen planus is satisfactory; it is cured within 2 to 6 months, but there are cases that evolve into chronic lesions and remain for years. This literature review was motivated by the need of updating the knowledge of students, dentists and physicians in our province.
Palabras clave : LICHEN PLANUS, ORAL [pathology]; LICHEN PLANUS, ORAL [immunology]; LICHEN PLANUS, ORAL [etiology]; STRESS; HLA-DR ANTIGENS.