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Revista Cubana de Farmacia
versión On-line ISSN 1561-2988
Resumen
VEGA, Maribel et al. Establecimiento de un material de referencia para interferón gamma humano recombinanteEstablishment of a reference material for human recombinant gamma interferon. Rev Cubana Farm [online]. 2005, vol.39, n.2, pp. 1-1. ISSN 1561-2988.
A production batch of human recombinant gamma interferon was characterized as reference material for different analytical techniques, and it was demonstrated by the different varianze analyses made for each of the assayed techniques that the batch fulfills the requirements to be used as reference material. The homogeneity study conducted by High Performance Liquid Chromatography technique in reverse phase showed that the reference material has the homogeneity required for its use. The batch is stable for 2 years stored at -70 °C, according to previous studies conducted in the production batches of active raw material of human recombinant gamma interferon
Palabras clave : Reference material; gamma interferon; working reference material.