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Revista Cubana de Medicina Tropical
versión On-line ISSN 1561-3054
Resumen
LEMUS MOLINA, Dihadenys et al. Resistance to tuberculosis drugs in Cuba, 2015-2017. Rev Cubana Med Trop [online]. 2021, vol.73, n.1 Epub 01-Abr-2021. ISSN 1561-3054.
Introduction:
Tuberculosis continues to be an important health problem worldwide. In the year 2016, as many as 600 000 cases of rifampicin resistance were estimated, among which 490 000 were multi-drug resistant.
Objective:
Describe the behavior of resistance to M. tuberculosis isolates in patients with pulmonary tuberculosis reported in Cuba in the period 2015-2017.
Methods:
Susceptibility to isoniazid and rifampicin was determined by the nitratase method. Susceptibility of rifampicin resistant / multi-drug resistant isolates to ofloxacin, kanamycin, amikacin and capreomycin was determined by the proportional method.
Results:
Of the isolates analyzed, 93.2% were sensitive to isoniazid and rifampicin. Isoniazid resistance was identified in 39 and 23 were rifampicin resistant. Ten multi-drug resistant isolates were identified. Resistance to second line drugs was not detected.
Conclusions:
Results warn about the need to study the factors leading to the increase in resistant tuberculosis in Cuba.
Palabras clave : tuberculosis; resistance; drugs.