Introduction:

Nesidioblastosis is a rare pancreatic condition that causes hypoglycemia due to endogenous hypersinsulinism in childhood. It is unusual in adults; only isolated cases have been published including its description.

Objective:

To characterize a case of hyperinsulinic hypoglycemia, in an adult patient with nesidioblastosis.

Clinical case:

A 35-year-old, white, male, adult patient with suspected insulinoma, with episodes of hypoglycemia in the fasting state or after exercise that was reversed with ingestion of food or glucose solutions. 85% pancreatectomy was performed and nesidioblastosis was detected in the histological study.

Conclusions:

It is rare in adults, making its diagnosis is difficult, and surgery is reached with the knowledge of an endogenous hyperinsulinic state, without the certainty of its origin.

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