Introduction:

Renal transplantation is one of the methods of renal function substitution and the main factor influencing survival is the immunological compatibility of the major system.

Objectives:

To define transplant survival and the relationship with the degree of compatibility.

Methods:

A retrospective study was carried out on the hospital-based survival time of 512 transplants from 1993 to 2010, including follow-up and the cut at the end of 2019. The Kaplan-Meier estimator was used to calculate the survivals, the statistical package Statistical Package Social Science (Spss) version 22.0 was used.

Results:

Three hundred ninety seven (397) patients received cadaveric kidneys at the cut, 11.3% of the grafts were functioning, 115 received living grafts, 45.2%, p=0.000. The median survival for the cadaveric kidneys was 3.1 years (SD 2.4-3.8) and among them those who shared three or more antigens achieved twice the survival, p=0.033. For the living donor, the median was 16.0 years (SD 9.1-22.9) and within this group, 104 patients, sharing a haplotype, achieved 44.2% function, siblings, who were identical, achieved 66 .0%. By kinship, those who received kidneys from siblings have better survival than for those who received it from parents, p=0.001.

Conclusions:

Immunological compatibility of the major system between donor and recipient was defined to favor differences in the function of the grafts.

        · resumen en Español     · texto en Español     · Español ( pdf )