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Revista Cubana de Medicina
versión On-line ISSN 1561-302X
Resumen
DIAZ LUIS, Osbel et al. Inflammatory pattern of the airways in COPD smokers. Rev. Cuban de Med [online]. 2023, vol.62, n.1 Epub 01-Mar-2023. ISSN 1561-302X.
Introduction:
Chronic obstructive pulmonary disease presents with an inflammatory pattern in the airway that includes neutrophils, macrophages, and lymphocytes, which can be obtained by cytological bronchial brushing.
Objectives:
To identify inflammatory pattern according to inflammatory cells present in the airway, through cytological bronchial brushing and smoking rate of packs/year in patients with chronic obstructive pulmonary disease.
Methods:
A cross-sectional descriptive study was carried out in patients with chronic obstructive pulmonary disease, who attended Benefico-Jurídico Pneumological Hospital, from June 2018 to June 2019, with an indication for fiberoptic bronchoscopy with bronchial brushing.
Results:
53.1% of the patients correspond to the male sex. 46.1% had a smoking rate of packs/year between 21-40. Crypts and striae predominated as bronchoscopic findings with 51% and 40.8% respectively in patients with a pack/year index greater than 40. Patients with a pack/year index greater than 40 (13 for 26.5%) showed basal cell hyperplasia. 46.9% of the patients had a neutrophilic inflammatory pattern.
Conclusions:
Patients with COPD who had a neutrophilic inflammatory pattern in the airway and high smoking index were identified, and from the bronchoscopic point of view they have several findings that suggest chronicity.
Palabras clave : bronchial brushing; cytology; signs of chronicity; bronchoscopic findings, inflammatory phenotype, smoking index.