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Revista Cubana de Medicina

versión On-line ISSN 1561-302X

Resumen

LOPEZ GONZALEZ, Franz Erich; JIMENEZ RAMIREZ, Rigoberto; RAMIREZ MENDEZ, Cesar Elias  y  SUAREZ PINA, Yorlin Melina. Proteinuria and Nephrotic Syndrome. Rev. Cuban de Med [online]. 2023, vol.62, n.1  Epub 01-Mar-2023. ISSN 1561-302X.

Introduction:

Nephrotic syndrome is a pathology that affects the glomerular complex of the kidney, characterized by proteinuria greater than 3500 mg/d. According to the response to steroids, nephrotic syndrome can be classified as steroid-resistant or steroid-sensitive.

Objective:

To determine the relationship between proteinuria and the variants of the nephrotic syndrome in adults.

Methods:

A descriptive, retrospective, case series type study was carried out with a population of 28 patients. The data was collected and processed through Epi-Info 7.2TM software; simple frequency, statistical mean, student's t-test, and Pearson's correlation coefficient.

Results:

The statistically significant difference was obtained in the antiproteinuric and non-statin group, between the mean post-treatment proteinuria of the steroid resistant nephrotic syndrome group (6202 mg/d) in comparison to steroid sensitive nephrotic syndrome (65.9 mg/d) (p value 0.0418). There is negative correlation between post-treatment proteinuria levels and post-treatment serum albumin level (r= -0.7 p value <0.00001).

Conclusions:

The absence of association between initial proteinuria and steroid-sensitive and steroid-resistant variants of nephrotic syndrome was demonstrated (p value=0.8).

Palabras clave : nephrotic syndrome; proteinuria; serum albumin; steroids; nephrology.

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