Resumen

GUERREIRO HERNANDEZ, Ana María et al. Prevalence and clinical significance of anti-SS-A(RO) antibodies in patients with systemic autoimmune rheumatic diseases. Rev Cubana Hematol Inmunol Hemoter [online]. 2017, vol.33, n.4, pp. 67-72. ISSN 1561-2996.

Due to the diagnostic importance of the detection of different antibody specificities that allows us to distinguish rheumatic syndromes that clinically overlap; we studied its prevalence in a group of 4 693 patients with systemic autoimmune rheumatic diseases In the period between June 10, 2010 and June 10, 2016. For that purpose we used ANA Screen and ANA Combi. 277 (5 %) were female and 250 male. There was a significant prevalence of anti-SS-A antibodies140 (50 %) followed by antinucleosome 97 (35 %) and DNAs of 72 (25 %), no significant results were obtained with the rest of the other antibodies. Our results suggest the usefulness of these tests in patients with clinical manifestations of systemic autoimmune rheumatic diseases together with the clinical and histological information that could help to make an accurate diagnosis.

Palabras clave : anti SS-A (RO) antibodies; systemic lupus erythematosus; Sjögrens syndrome; immunoenzymatic assay.

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