Background:

the giant cell tumor of the tendon sheath occupies the second place in frequency in the neoplasms of the hand. The diagnosis is clinical and radiological, confirmed by anatomic-pathological studies.

Objective:

to describe the epidemiology, clinical and histological aspects of the giant cell tumor of the tendon sheath.

Methods:

a descriptive observational study was carried out for the report of six cases from the files of the Department of Pathology from 2016 and 2018, to identify the cases with a diagnosis of giant cell tumor of the tendon sheath.

Results:

a total of six cases of giant cell tumor of the tendon sheath were diagnosed, corresponding 50% to each sex; the majority were under 40 years old; and in all cases the site of presentation of the tumor was the hand; with a predominance in the palm region of the thumb. None of the cases manifested pain. In the morphological study, the characteristic histological elements of the giant cell tumor of the tendon sheath were observed microscopically.

Conclusions:

the six patients studied presented the typical symptoms of the Giant cell tumor of the tendon sheath, referring to an increase in volume that was corroborated with the physical examination by palpating a mass of subcutaneous, non-painful, smooth, soft tissue with well-defined borders. In the same way, histopathologically, the characteristic morphological elements were corroborated, for which it can be established that there was a clinical-pathological correlation of 100%.

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