SciELO - Scientific Electronic Library Online

 
vol.25 número2Tumor de células granulares: a propósito de un casoManiobras de movilización visceral en el trauma vascular abdominal índice de autoresíndice de materiabúsqueda de artículos
Home Pagelista alfabética de revistas  

Servicios Personalizados

Articulo

Indicadores

  • No hay articulos citadosCitado por SciELO

Links relacionados

  • No hay articulos similaresSimilares en SciELO

Compartir


Revista Archivo Médico de Camagüey

versión On-line ISSN 1025-0255

Resumen

AGUILAR-GAMBOA, Franklin Rómulo; VEGA-FERNANDEZ, Jorge Arturo  y  SUCLUPE-CAMPOS, Danny Omar. SARS-COV-2: more than a respiratory virus. AMC [online]. 2021, vol.25, n.2  Epub 01-Abr-2021. ISSN 1025-0255.

Background:

the SARS-CoV-2 virus is responsible for the second pandemic of the 21st century. Since its appearance in China at the end of 2019, it has been associated with pneumonia and considered to be just another respiratory virus. However, during its global spread, it shows its ability to damage other organs with clinical manifestations never before described for other respiratory viruses.

Objective:

to describe the scientific evidence that supports the direct extra-pulmonary damage produced by the SARS-CoV-2 virus in late stages of infection, which supports its biphasic nature and different from other respiratory viruses.

Methods:

a search of the articles was carried out in the MEDLINE databases accessed from PubMed, SciELO and LILACS. Articles published in prepress repositories such as medRxiv, BioRxiv were also taken into account. Using the Mendeley reference manager and search manager, duplicates and those that did not meet the objective of the study were eliminated, selecting 63 articles for the present review.

Results:

the evidence suggests that SARS-CoV-2 has a tropism not only limited to the respiratory tract. The clinical progression of COVID-19 presents a biphasic course, with flu-like manifestations in the first phase and post-acute and persistent episodes in the late phase, caused by direct damage to the central nervous, cardiovascular, endocrine and renal systems.

Conclusions:

SARS-CoV-2 infection should not be considered only as an acute infection limited to the respiratory tract.

Palabras clave : SARS VIRUS/pathogenicity; CORONAVIRUS INFECTIONS/transmission; RESPIRATORY TRACT INFECTIONS/prevention & control; VIRAL TROPISM/physiology; VIRUS REPLICATION.

        · resumen en Español     · texto en Español     · Español ( pdf )