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Revista Información Científica
versión On-line ISSN 1028-9933
Resumen
NOA-SUAREZ, Dalenia y VAZQUEZ-BALART, Liuvia. Drug-resistant tuberculosis in Guantánamo province, 2010-2019. Rev. inf. cient. [online]. 2021, vol.100, n.4 Epub 24-Jun-2021. ISSN 1028-9933.
Introduction:
An increase in the number of drug-resistant tuberculosis patients has been observed in the last 10 years in Cuba and, especially, in Guantánamo province. This is the province with the highest incidence in the country.
Objective:
To identify the epidemiological characteristics and the resistance pattern of drug-resistant tuberculosis in Guantánamo province.
Method:
A descriptive, cross-sectional study was designed that included all cases (n=6) with drug-resistant tuberculosis, diagnosed between December 2010 and December 2019. The variables studied were: age, gender, therapeutic regimen, economic situation, categories of cases, epidemiological classification of resistance, and resistance of the isolated strain according to the grade and profile.
Results:
Males predominated (66.6%), and also the age group under 45 years (83.3%), the greatest resistance was caused by not abiding the previous treatments (66.6%), categorized mostly as chronic, and readmitted due to treatment abandonment. Highschool degree (66.7%) predominated, with a moderate economic situation (50.0%) and high levels of alcoholism (66.7%). Multi-drug resistance prevailed in the strains in patients with previous treatment (66.6%).
Conclusions:
There is a coincidence of the epidemiological pattern and the resistance pattern shown in the current research with the results of previous national and international studies; these results suggest flaws in the local application of the Programa Nacional de Control y Tratamiento de la tuberculosis. It is recommended to investigate and resolve these flaws, which would have an immediate impact on reducing the incidence of drug-resistant tuberculosis.
Palabras clave : tuberculosis; drug resistance; multidrug resistance.