Resumen

BUSTILLO SOLANO, Emilio; DENIS CANCIO, Humberto  y  BUSTILLO SOLANO, Iván. Long-term benefit of the Therapeutic Program of Diabetic Nephropathy. Rev Cubana Endocrinol [online]. 2001, vol.12, n.3, pp. 158-167. ISSN 1561-2953.

A therapeutic program of diabetic nephropathy was applied to 2 different groups of type I diabetic patients (group A: 1990-1999, group B: 1995-1999), both in proteinuric stages. It was proved that a decade after the beginning of the therapeutic program, a subgroup of patients from group A (late proteinuric stage) delayed their evolution towards end-stage chronic kidney failure. The accumulative mortality of these patients was 44.7 % LC-95 %: 28.9-60.5 %. Uremia was considered as the main cause of death. Applying the threapeutic program to diabetic patients in the late proteinuric stage, during the first 5 years of treatment, represented a relative risk for end-stage chronic kidney failure and/or kidney substitutive treatment of 5.3 (LC-95 %: 1.23-22.8) and a higher death risk (RR:2.6 LC-95 %: 1.01-6.7) compared with those patients that were not included in this program (group B). It was concluded that the therapeutic program has contributed to improve the survival and quality of life of a subgroup of type I diabetic patients with clinical diabetic nephropathy.

Palabras clave : DIABETIC NEPHROPATHIES [complications]; DIABETES MELLITUS, INSULIN DEPENDENT; KIDNEY FAILURE, CHRONIC; QUALITY OF LIFE; PROTEINURIA.

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