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Revista de Ciencias Médicas de Pinar del Río
versión On-line ISSN 1561-3194
Resumen
PINEDA-DANIEL, Oderkys; FORTUN-PRIETO, Adalberto; CARBALLO-GUTIERREZ, Javier Luis y HERNANDEZ-LUIS, José Jairan. Acute tubulointerstitial nephritis due to cephalexin. Apropos of a case. Rev Ciencias Médicas [online]. 2022, vol.26, n.6 Epub 01-Nov-2022. ISSN 1561-3194.
ABSTRACT
Introduction:
acute tubulointerstitial nephritis refers to a type of renal damage that mainly affects the interstitium and causes potentially reversible acute injury. Its course may be subclinical or with progressive deterioration, until it evolves into chronic renal disease. Its management includes the suspension of the responsible drug and the use of steroids when the condition is of drug or autoimmune origin. If identified in a timely manner and adequately treated, its prognosis is generally favorable.
Case presentation:
we report a young patient with a history of good health, who after a stomatological procedure received treatment with oral cephalexin for seven days and developed acute tubulointerstitial nephritis clinically and histologically proven that responded satisfactorily to the usual treatment of the disease, which indicates the need to take into account its possibility, even in usual clinical situations, and increase the knowledge of medical professionals about this disorder that can even be a cause of chronic kidney disease and avoid the use of antibiotics when they are not a strict necessity.
Conclusions:
acute tubulointerstitial nephritis is a complication that may be present after the use of cephalosporins, including those of the first generation administered orally, in the treatment of common diseases with a favorable prognosis.
Palabras clave : ACUTE KIDNEY INJURY; NEPHRITIS, INTERSTITIAL; CEPHALEXIN; BIOPSY.