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Anales de la Academia de Ciencias de Cuba
versión On-line ISSN 2304-0106
Resumen
CAPO DE PAZ, Virginia et al. Autopsy findings in a series of 50 decedents with sars-cov-2 infection, in Cuba, from April to September 2020. Anales de la ACC [online]. 2021, vol.11, n.2 Epub 01-Ago-2021. ISSN 2304-0106.
Introduction:
Post mortem studies are essential during epidemics of unknown etiology. Objective: to characterize the histopathological findings of autopsies performed during the SARS-CoV-2 pandemic.
Methods:
this is a series of case study of minimally invasive autopsies of 50 decedents positives for SARS-CoV-2 infection that occurred from April to September 2020.
Results:
COVID-19 was the basic cause of death for 27 decedents (54%) and the contributing cause for 6 cases (12%). The acute lung damage predominated, followed by acute kidney injury (78%); small vacuoles fatty liver (54%), and focal mild to moderate myocarditis (18%). The presence of viral antigens in the alveolar, bronchiolar and renal tubular epithelial cells was detected. Conclusions: The minimally invasive autopsy became a practical and useful method for SARS-CoV-2 (COVID-19) decedents but usual biosafety precautions should be reinforced in order to avoid generation of aerosols.
Palabras clave : autopsies; COVID-19; histopathological findings; Cuba.