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Revista Información Científica
versión On-line ISSN 1028-9933
Resumen
URGELLES-RODRIGUEZ, Eduardo; LEGRA-LOPEZ, Hormanis y RICARDO-CHACON, Omar Abel. Salivary pH as diagnostic biomarker in patients diagnosed with oral squamous cells carcinoma in Guantanamo. Rev. inf. cient. [online]. 2022, vol.101, n.4 Epub 20-Oct-2022. ISSN 1028-9933.
Introduction:
Oral cancer is a common health problem worldwide.
Objective:
Compare the salivary pH range changes among patients diagnosed recently with oral squamous cells carcinoma after receiving oncospecific treatment and subjects apparently healthy, Guantanamo, Cuba, period time November 2019 -January 2022.
Method:
A descriptive, comparative, cross-sectional study was carried out in outpatients of the Maxillofacial Surgery Consultation room at the Hospital General Docente "Dr. Agostinho Neto". The study group consisted of 200 patients divided into 3 subgroups: subgroup I (50 newly diagnosed patients with oral squamous cell carcinoma, with concomitant diagnosis of dental caries and chronic adult periodontitis); subgroup II (50 patients with the aforementioned pathology after oncospecific treatment, treated for the aforementioned oral diseases) and subgroup III (100 apparently healthy control patients). The following variables were studied: age, sex, type of diet and salivary pH.
Results:
Average age was 59.8 years, 70% were men. There was an association between the diet consumed and each subgroup (p= 0.001). The salivary pH of newly diagnosed squamous cell carcinoma patients affected by both oral diseases was acidic (6.25±0.37) compared to the other subgroups. The 98.6% of patients with acid salivary pH presented a usual diet based on carbohydrates and fats (p=0.000).
Conclusions:
It was shown that the salivary pH of newly diagnosed patients with squamous cell carcinoma was acidic compared to the other subgroups. Therefore, this parameter can be used as a biological marker of the disease.
Palabras clave : oral cancer; epidermoid carcinoma; diet, salivary pH, oncospecific, dental caries, periodontopathies.