Resumen

CEDENO MIRANDA, Aleida; MARQUEZ CAMAYD, Jorge Enrique  y  TAMAYO SERRANO, Jesús Rene. Presentation of a patient with stevens-johnson syndrome / toxic epidermal necrolysis. CCM [online]. 2014, vol.18, n.4, pp. 793-799. ISSN 1560-4381.

Six years old, mixed race school girl patient, with a health record, no family history to note, was presented. Born from a normal pregnancy and a delivery at term. Properly fed, well immunized. Good growth and development. The patient had come to her family physician because of cold symptoms with persistent cough and fever; she received a medication with phenytoin among other drugs. On the second day of treatment the patient developed cutaneous manifestations of blisters that exposed, when opened, erythematous and humid areas that extended to almost the entire body surface. The Stevens - Johnson syndrome is a potentially fatal skin disease characterized by extensive epidermal and mucosal necrosis that is accompanied by malaise. Stevens Johnson Syndrome and toxic epidermal necrolysis are hypersensitivity reactions that are considered clinic and pathologic entity of the same polar forms. Both Stevens-Johnson syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are severe cutaneous adverse reactions associated with some medications (RACS). These conditions have significant impact on public health because of its high morbidity and mortality. The percentage of affected skin surface classifies this disease into three groups and could define the prognosis: -SSJ, when it affects less than 10% body surface - Overlapping SSJ-NET of 10-30% - NET, greater than 30% skin detachment.

Palabras clave : Stevens-Johnson syndrome; toxic epidermal necrolysis; dermatitis; hypersensitivity; adverse drug reaction.

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