Introduction:

Platelet-rich fibrin (PRF) is considered a regenerative material that possesses a large amount of growth factors, leukocytes, platelets and cytokines that are required in healing processes. In dentistry, it is a growing trend due to its versatility, especially in oral and maxillofacial surgery, oral implantology and periodontics.

Methods:

The methodology used was PRISMA Preferred Reporting Items for Systematic reviews and Meta-Analysis Protocols, where the search criteria were met according to Cochrane standards for systematic reviews. In addition, the Perish or Perish tool was used for data extraction, in order to carry out this search for articles related to the object of study.

Development:

platelet-rich fibrin is obtained by centrifugation of the patient's own blood without artificial biochemical modification. Among its main properties are the stimulation of osteoblast differentiation and proliferation, stimulation of angiogenesis and mitogenic effect. It has a wide use in the field of dentistry. In periodontics and oral implantology it has multiple applications, to treat gingival recessions, in maxillary sinus floor elevation, increases the effect of coagulation/tissue regeneration at the surgical site by means of a natural clot that accelerates the healing of soft and hard tissues.

Conclusions:

It is concluded that the benefits of FRP in the recovery of patients, therefore, the feasibility of its use in different procedures, whether they are periodontics, endodontics, surgery or easy harmonization, is evidenced.

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