Resumen

SOSA MARTIN, Gimel; MARTINEZ VALENZUELA, Noslen  y  MORALES PORTUONDO, Kelvis. Acute appendicitis:. Rev Cubana Cir [online]. 2009, vol.48, n.3, pp. 0-0. ISSN 1561-2945.

INTRODUCTION: Acute appendicitis if the affection that more frequent requires of an emergence surgical intervention. Use of antimicrobial prophylaxis decreases sepsis incidence of surgical wound, and to improve the risk-benefit and the cost-benefit relation of surgery. Present study tried to design and to creates a therapeutical protocol for use of antimicrobials, according to acute appendicitis stage to use in secondary care centers. METHODS: We made a prospective study of prescription-indication with the elements of practical consequences, and an intervention group. We randomly selected 215 patients diagnosed with acute appendicitis, seen from December 2002 to December 2006. Two groups were designed: one as control and another of experimental type. We set a prophylactic protocol in experimental group based on reference texts and adjusted to the Cuban socioeconomic context. RESULTS: Prophylaxis protocol was applied to 105 patients. Sepsis incidence was of 8,5%, lower than control group (24,5%). Cost was lower too in experimental group. CONCLUSIONS: Rational use of antimicrobial therapeutics for prophylaxis of surgical wound improves the risk-benefit and the cost-benefit relations of surgical procedure and quality of medical care.

Palabras clave : Perioperative antibiotic therapy; acute appendicitis..

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