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MEDISAN

versión On-line ISSN 1029-3019

Resumen

FERNANDEZ ALVAREZ, Haron. Clinical epidemiological characterization of patients with types A and B congenital hemophilia in Santiago de Cuba. MEDISAN [online]. 2022, vol.26, n.3  Epub 08-Jun-2022. ISSN 1029-3019.

Introduction:

The hemophilia is a disease of genetic origin, linked to chromosome X that affects the natural capacity of the blood to form a clot, due to the absence, decrease or a defective operation of the factors VIII and IX, hence the types A and B, respectively.

Objective:

To describe the clinical and epidemiologic characteristics of patients with types A and B congenital hemophilia in Santiago de Cuba.

Method:

A descriptive and cross-sectional study of the 41 patients with types A and B congenital hemophilia (in a pediatric and adults population) assisted in the hemostatic disorders service of Dr. Juan Bruno Zayas Alfonso Teaching General Hospital in Santiago de Cuba, was carried out from November, 2017 to December, 2018.

Results:

In the series there was a prevalence of young adults with hemophilia A (56.1 %), moderate hemophilia (58.6 %), light articular lesion (36.6 %), the cryoprecipitate as the most used treatment and the secondary school level.

Conclusions:

The hemophilia A was the most frequent, in young adults residents in Santiago de Cuba municipality, mainly that of moderated type and with light arthropathy. There were no differences related to the national and international reports and the study of the genetic and molecular disorders was limited by the technological conditions of the moment.

Palabras clave : hemophilia; hemophilia A; hemophilia B; epidemiology.

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