Introduction:

physalis peruviana, also known as uvilla or uchuva, is a plant native to South America that has been traditionally used for its medicinal properties.

Objective:

to describe the biological activity of Physalis peruviana and its therapeutic potential.

Methods:

an exhaustive review of the scientific literature available in the electronic databases PubMed, Scopus and Web of Science was carried out. A filter was applied to limit the results to articles published in the last five years, obtaining a total of 28 articles available in the database. English-language articles were selected that focused on the biological activity of Physalis peruviana.

Results:

the plant contains bioactive compounds, such as withanolides, flavonoids, phenolic acids and carotenoids, which contribute to its therapeutic properties. Some studies have shown the efficacy of Physalis peruviana in the regulation of serum glucose levels, prevention of tumor formation and protection against oxidative damage, including its potential as an antidiabetic, anti-inflammatory, anticancer, antioxidant, antibacterial, neuroprotective and nephroprotective agent.

Conclusions:

physalis peruviana is a promising source of bioactive compounds with diverse therapeutic properties, such as antidiabetic, anticancer, antioxidant, antibacterial, neuroprotective and nephroprotective activity. The findings underscore the importance of continuing research in this area to discover and develop new natural products that can be used in the prevention and treatment of various diseases.

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