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Revista Cubana de Farmacia
versão On-line ISSN 1561-2988
Resumo
LEMUS RODRIGUEZ, Zoe; RODRIGUEZ CARBONELL, Aimée; VISTEL VIGO, Marlen e CHONG QUESADA, Amaury. Escalado por modelación en la producción farmacéutica. Rev Cubana Farm [online]. 1998, vol.32, n.1, pp. 7-12. ISSN 1561-2988.
The scale-up of the mixing and drying processes in studies according to the technological flow installed in a pharmaceutical production laboratory, making use of the resemblance principle (rigorous for mixing and extrapolated for drying), which is the basis of the theory of models. Conveniently validated scale ecuations are obtained from the applied methodologies, allowing to predict, starting from the laboratory, the behaviour of the processes under consideration.
Palavras-chave : TECHNOLOGY, PHARMACEUTICAL [methods]; MODELS, THEORETICAL; DRUG INDUSTRY; DRUG DESIGN.