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Nucleus
versão impressa ISSN 0864-084X
Resumo
HERNANDEZ GONZALEZ, Ignacio. Non clinical research at CENTIS supporting biotechnological and pharmaceutical industry . Nucleus [online]. 2012, n.52, pp. 35-40. ISSN 0864-084X.
Drugs production is a highly demanding industry because of the high rigor of current regulations and standards which apply to manufacturing facilities. They are also required in the research and development stage. Our national biotechnological industry is developing and producing important drugs for national and international market to treat diseases like cancer. The Isotope Centre is an institution supporting such a development by means of a work platform to carry out researches in the field of pharmacokinetic and biodistribution in experimental models. Accumulated experience allows us to contribute to research and development of different kind of products (i.e. biotechnological), what represents a move towards the development of new technologies and the incorporation of appropriate methodologies to current standards. Radiolabeling is still a convenient choice to obtain images of drug distribution and kinetics. With the techniques currently available and those to be used in a near future, we can undertake to the most important researches required.
Palavras-chave : peptides; monoclonal antibodies; image processing; drugs; standards; manufacturing.