Resumo

ADDINE RAMIREZ., Bárbara de la Caridad et al. Demography and immunology of phenotypic variants of allergy in atopic patients aged 1-5 years. Granma. 2012-2018. Multimed [online]. 2020, vol.24, n.2, pp. 259-277.  Epub 23-Abr-2020. ISSN 1028-4818.

An analytical study was carried out in the Allergy Service of the Ambulatory Medical Center of Granma, in the period 2012-2018, with the aim of demographically and immunologically characterizing the phenotypic variants of allergy in 224 patients from 1 to 5 years of age. Age, sex, IgA, IgG and IgE value, complement components C3 and C4, total leukogram value, and eosinophils in blood and nasal mucosa were studied, as well as the clinical diagnosis of each phenotypic variant of allergy. Statistical processing included descriptive statistics. In addition, inferential statistics was used in the performance of bivariate analyzes through CHI 2 to identify an association with p <0.05. There were no differences in terms of sex and children of 4 and 5 years of age predominated. The order of frequency of the different phenotypes of allergic diseases was, from highest to lowest, allergic rhinitis, bronchial asthma, allergic conjunctivitis and atopic dermatitis. In the patients studied, elevated IgE and eosinophil values ​​predominated in nasal and blood cytology and normal IgA, IgG, C3, C4 and total leukocyte count.

Palavras-chave : Allergies; Hypersensitivity; Asthma; Allergic rhinitis; Atopic dermatitis; Allergic conjunctivitis.

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