Resumo

PEREZ BORREGO, Amparo; GUNTINAS ZAMORA, María Victoria  e  GONZALEZ LABRADA, Carelia. Estomatitis aftosa recurrente: Determinación de marcadores de inmunidad celular. Rev Cubana Estomatol [online]. 2002, vol.39, n.2, pp. 75-88. ISSN 1561-297X.

Recurrent aphthous stomatitis, oral aphthosis or aphthae is the most frequent of all oral mucosal membrane diseases. Its etiology and pathogenesis are not totally known but genetic, food, infectious, allergic, drug, trauma and immunological factors are involved. We studied 51 patients who suffered from this disease and were seen at the Maxillofacial Surgery Department of "William Soler" Pediatric Hospital. Our objective was to assess the cell immunocompetence by determining the percentage of active and spontaneous rosette-forming cells. The average age of the group was 12 years, both sexes were equally affected but white patients greatly prevailed over black patients. At least one immunoresponse marker of 73% of the patients was affected; 25 patients had both markers under the normal parameters and 12 cases presented with disturbances in one of the two markers. It was concluded that the disease is linked to cell immunity defects, which should be considered in the treatment, taking into account that no curative drug is so far available.

Palavras-chave : STOMATITIS, APHTHOUS [immunology]; STOMATITIS, APHTHOUS [etiology]; IMMUNITY, CELLULAR; IMMUNOCOMPETENCE; CHILD.