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Revista Cubana de Medicina
versão On-line ISSN 1561-302X
Resumo
LOPEZ RAMIREZ, Mirtha; GUAYAULEMA CUDCO, Patricia Elizabeth e TAMARGO BARBEITO, Teddy Osmin. Myocardial Damage in COVID-19. Rev. Cuban de Med [online]. 2023, vol.62, n.4 Epub 15-Mar-2024. ISSN 1561-302X.
Introduction:
Coronavirus disease has caused myocardial damage. This reality has impacted medical sciences and it has been the subject of research.
Objective: To show, through the results of recent research, the mechanisms by which the SARS-CoV-2 virus produces myocardial damage in patients affected by COVID-19, and its influence on short- and long-term prognosis.
Methods:
A bibliographic search was carried out of the updated medical literature on the topic published in English and Spanish, indexed in several databases from May 2019 to May 2022. One hundred ninety-eight articles were included in the review, only 78 met the selection criteria. Those that did not contain precise information regarding myocardial damage caused by SARS-CoV-2 were excluded.
Results:
Several mechanisms have been described as probable triggers, standing out direct damage by angiotensin II, hypoxia-induced injury, myocardial microvascular damage and systemic inflammatory response syndrome.
Conclusions:
The different mechanisms by which SARS-CoV-2 virus produces myocardial damage make COVID-19 patients more likely to suffer myocardial injury. Clinical manifestations in COVID-19 patients such as myocarditis, heart failure, cardiac arrhythmias, acute coronary syndrome and pericardial effusion are more common in patients with history of cardiovascular disease, which do not favors their prognosis.
Palavras-chave : coronavirus infections; myocardial damage; myocardial injury COVID-19, SARS-CoV-2.