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Revista Cubana de Pediatría
versão On-line ISSN 1561-3119
Resumo
VELIZ JORNA, Ana Laura; ARAUJO HERRERA, Orlando e AVILA OCHOA, Ivonne. Type 1 diabetes mellitus and celiac disease in children and adolescents. Rev Cubana Pediatr [online]. 2022, vol.94, n.3 Epub 20-Jul-2022. ISSN 1561-3119.
Introduction:
The association between celiac disease and type 1 diabetes mellitus has been published more frequently than isolated celiac disease, whose natural history can vary considerably, with evidence of gastrointestinal symptoms in the minority of patients.
Objective:
To characterize patients with type 1 diabetes mellitus and celiac disease.
Method:
Observational, descriptive and cross-sectional study in 63 children treated at "Centro Habana" Pediatric Teaching Hospital between the years 2016-2017 with a diagnosis of type 1 diabetes mellitus. The variables studied were expressed in absolute and relative values, a measure of central tendency and dispersion.
Results:
Males accounted for 58.73% of the patients, most of them between 10 and 14 years old. The anti-transglutaminase antibody was positive in less than 10% of the children, usually without symptoms, signs, or findings related to celiac disease. The frequency of both diseases in the patients studied was 3.17%.
Conclusions:
Type 1 diabetes mellitus predominates in males unlike celiac disease which is diagnosed in female patients. The results of anti-transglutaminase antibodies are negative in most patients while the positive ones have more than a year of evolution of diabetes, are eutrophic or overweight, asymptomatic and with slightly higher values of glycosylated hemoglobin.
Palavras-chave : type 1 diabetes mellitus; celiac disease; children and adolescents.