Resumo

CAPOTE LEYVA, Eliseo et al. Serotonin syndrome secondary to the use of paroxetine in a patient under systematic hemodiálisis regime. Rev Cub Med Mil [online]. 2009, vol.38, n.1, pp. 0-0. ISSN 1561-3046.

Serotonin syndrome is a clinical situation characterized by altered state of mind, autonomic instability and neuromuscular anomalies such as tremor, hyperreflexia or myoclonia, which are symptoms that may occur as a result of the use of drugs that increase serotonin levels when acting as selective serotonin reuptake inhibitors or their association with other drugs as monoaminoxidase inhibitors. This paper presented the case of a 78 years-old female patient suffering from terminal chronic renal failure caused by hypertension, low therapy of periodic hemodyalisis which gave rise to serotonin syndrome secondary to the daily use of 20 mg paroxetine prescribed for a depression condition. Infectious, metabolic, neurological diseases as well as some drug overdose were ruled out. The patient improved her condition after paroxetine treatment was suspended.

Palavras-chave : Serotonin syndrome; paroxetine; chronic renal failure; hemodyalisis..

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